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S7 research desk

Fresh perspectives. Research made clearer.

Explore our latest articles, followed by five original S7 research guides. The five guides translate official labeling and peer-reviewed research into plain language, with new editions every Wednesday.

Five research guides updated weeklyWednesday morningsSources shown with every guide

Featured article

Build the Metabolism. Build the Muscle. Cut the Fat?

Exploring the connections between energy, muscle, and fat metabolism through MOTS-c, SLU-PP-332 and AOD-9604 research.

September 11, 20269 min read
Read on S7 Sciences

Latest reading

Read the complete article here.

Start with the latest Soro-powered articles. Our five weekly guides follow, each crediting the original authors and publication and linking to the complete sources and supporting evidence.

01
Latest articlesPowered by Soro

From the S7 journal.

Browse new articles as they are published through our Soro feed.

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02
S7 Sciences
Men’s health evidence3 min read

Featured articleKisspeptin modulates sexual and emotional brain processing in humans

A controlled experiment in healthy men offers a lesson in separating a brain response from a lasting benefit.

An imaging result can help explain a biological mechanism without establishing that a treatment improves everyday sexual health.

Updated October 28, 20263 min readSources shown with every article
Read on S7 Sciences
03
S7 Sciences
Women’s health evidence3 min read

Featured articleLiraglutide 3 mg on weight, body composition, and hormonal and metabolic parameters in women with obesity and polycystic ovary syndrome: a randomized placebo-controlled-phase 3 study

A placebo-controlled liraglutide study shows why outcome improvements and adverse events belong in the same summary.

A favorable average outcome does not erase side effects or tell every woman what her individual result will be.

Updated October 28, 20263 min readSources shown with every article
Read on S7 Sciences
04
S7 Sciences
Lab math3 min read

Featured articleLimit of quantification

Reading a concentration report means preserving limits, units and uncertainty instead of turning every entry into an exact number.

A less-than result gives a boundary under a stated method. Replacing it with zero invents information the report did not supply.

Updated October 28, 20263 min readSources shown with every article
Read on S7 Sciences
05
S7 Sciences
Evidence guide3 min read

Featured articleTriple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial

An imaging substudy illustrates the difference between measuring liver fat and demonstrating recovery from liver disease.

A lower MRI fat measurement is a specific finding. It should not be rewritten as proven reversal of fibrosis or prevention of liver complications.

Updated October 28, 20263 min readSources shown with every article
Read on S7 Sciences
06
S7 Sciences
Long-term evidence3 min read

Featured articleEffect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial

A randomized withdrawal trial shows why the people entering a study and those entering its main comparison are not always the same group.

A maintenance result applies most directly to the participants who reached randomization. It does not turn the trial's calendar into a personal cycle.

Updated October 28, 20263 min readSources shown with every article
Read on S7 Sciences

Soro archive

Previous Soro articles.

Rolling archive

Previous weekly editions.

Editions remain listed here for 3 months. Saved article links continue to work.

Featured sources are listed once. Choose a dated edition to read that week's S7 article and see the sources added in that update.

S7 Sciences

Kisspeptin-10 Is a Potent Stimulator of LH and Increases Pulse Frequency in Men

The Journal of Clinical Endocrinology & Metabolism

Published October 21, 2026
Previous weekly editions.
  • Published October 21, 2026Evidence updated

    Sources added in this edition

    • Kisspeptin-10 Is a Potent Stimulator of LH and Increases Pulse Frequency in Men
S7 Sciences

Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilization

The Journal of Clinical Investigation

Published October 21, 2026
Previous weekly editions.
  • Published October 21, 2026Evidence updated

    Sources added in this edition

    • Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilization
S7 Sciences

Mass concentration

IUPAC Compendium of Chemical Terminology, fifth edition, online version 5.0.0

Published October 21, 2026
Previous weekly editions.
  • Published October 21, 2026Evidence updated

    Sources added in this edition

    • Mass concentration
    • Amount concentration
S7 Sciences

Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial

JAMA Psychiatry

Published October 21, 2026
Previous weekly editions.
  • Published October 21, 2026Evidence updated

    Sources added in this edition

    • Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial
S7 Sciences

Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial

Nature Medicine

Published October 21, 2026
Previous weekly editions.
  • Published October 21, 2026Evidence updated

    Sources added in this edition

    • Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial
S7 Sciences

Chronic subcutaneous kisspeptin-10 stimulates gonadotropin secretion for 12 days in healthy men

European Journal of Endocrinology

Published October 14, 2026
Previous weekly editions.
  • Published October 14, 2026Evidence updated

    Sources added in this edition

    • Chronic subcutaneous kisspeptin-10 stimulates gonadotropin secretion for 12 days in healthy men
S7 Sciences

Once-weekly semaglutide versus placebo in adults with increased fracture risk: a randomised, double-blinded, two-centre, phase 2 trial

EClinicalMedicine

Published October 14, 2026
Previous weekly editions.
  • Published October 14, 2026Evidence updated

    Sources added in this edition

    • Once-weekly semaglutide versus placebo in adults with increased fracture risk: a randomised, double-blinded, two-centre, phase 2 trial
S7 Sciences

Calibration of future measurements

NIST/SEMATECH e-Handbook of Statistical Methods, section 2.3.6.6

Published October 14, 2026
Previous weekly editions.
  • Published October 14, 2026Evidence updated

    Sources added in this edition

    • Calibration of future measurements
S7 Sciences

Tirzepatide for Metabolic Dysfunction-Associated Steatohepatitis with Liver Fibrosis

New England Journal of Medicine

Published October 14, 2026
Previous weekly editions.
  • Published October 14, 2026Evidence updated

    Sources added in this edition

    • Tirzepatide for Metabolic Dysfunction-Associated Steatohepatitis with Liver Fibrosis
S7 Sciences

Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes

New England Journal of Medicine

Published October 14, 2026
Previous weekly editions.
  • Published October 14, 2026Evidence updated

    Sources added in this edition

    • Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes
S7 Sciences

Kisspeptin Administration Stimulates Reproductive Hormones but Does Not Affect Anxiety in Humans

The Journal of Clinical Endocrinology & Metabolism

Published October 7, 2026
Previous weekly editions.
  • Published October 7, 2026Evidence updated

    Sources added in this edition

    • Kisspeptin Administration Stimulates Reproductive Hormones but Does Not Affect Anxiety in Humans
S7 Sciences

Effects of combined metformin and semaglutide therapy on body weight, metabolic parameters, and reproductive outcomes in overweight/obese women with polycystic ovary syndrome: a prospective, randomized, controlled, open-label clinical trial

Reproductive Biology and Endocrinology

Published October 7, 2026
Previous weekly editions.
  • Published October 7, 2026Evidence updated

    Sources added in this edition

    • Effects of combined metformin and semaglutide therapy on body weight, metabolic parameters, and reproductive outcomes in overweight/obese women with polycystic ovary syndrome: a prospective, randomized, controlled, open-label clinical trial
S7 Sciences

Evaluating, Expressing, and Propagating Measurement Uncertainty for NIST Reference Materials

National Institute of Standards and Technology, Special Publication 260-202

Published October 7, 2026
Previous weekly editions.
  • Published October 7, 2026Evidence updated

    Sources added in this edition

    • Evaluating, Expressing, and Propagating Measurement Uncertainty for NIST Reference Materials
S7 Sciences

Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial

JAMA

Published October 7, 2026
Previous weekly editions.
  • Published October 7, 2026Evidence updated

    Sources added in this edition

    • Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial
S7 Sciences

Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes

New England Journal of Medicine

Published October 7, 2026
Previous weekly editions.
  • Published October 7, 2026Evidence updated

    Sources added in this edition

    • Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes
S7 Sciences

Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial

Human Reproduction

Published September 30, 2026
Previous weekly editions.
  • Published September 30, 2026Evidence updated

    Sources added in this edition

    • Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial
S7 Sciences

Efficacy of Semaglutide by Sex in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Trials

Journal of the American College of Cardiology

Published September 30, 2026
Previous weekly editions.
  • Published September 30, 2026Evidence updated

    Sources added in this edition

    • Efficacy of Semaglutide by Sex in Obesity-Related Heart Failure With Preserved Ejection Fraction: STEP-HFpEF Trials
S7 Sciences

Bias and Accuracy

NIST/SEMATECH e-Handbook of Statistical Methods, section 2.1.1.3

Published September 30, 2026
Previous weekly editions.
  • Published September 30, 2026Evidence updated

    Sources added in this edition

    • Bias and Accuracy
S7 Sciences

Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity

New England Journal of Medicine

Published September 30, 2026
Previous weekly editions.
  • Published September 30, 2026Evidence updated

    Sources added in this edition

    • Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity
S7 Sciences

Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes

New England Journal of Medicine

Published September 30, 2026
Previous weekly editions.
  • Published September 30, 2026Evidence updated

    Sources added in this edition

    • Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes
S7 Sciences

Effects of liraglutide on obesity-associated functional hypogonadism in men

Endocrine Connections

Published September 23, 2026
Previous weekly editions.
  • Published September 23, 2026Evidence updated

    Sources added in this edition

    • Effects of liraglutide on obesity-associated functional hypogonadism in men
S7 Sciences

Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis

New England Journal of Medicine

Published September 23, 2026
Previous weekly editions.
  • Published September 23, 2026Evidence updated

    Sources added in this edition

    • Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis
S7 Sciences

Metrological Traceability: Frequently Asked Questions and NIST Policy

National Institute of Standards and Technology

Published September 23, 2026
Previous weekly editions.
  • Published September 23, 2026Evidence updated

    Sources added in this edition

    • Metrological Traceability: Frequently Asked Questions and NIST Policy
S7 Sciences

Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes

New England Journal of Medicine

Published September 23, 2026
Previous weekly editions.
  • Published September 23, 2026Evidence updated

    Sources added in this edition

    • Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
S7 Sciences

3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial

The Lancet

Published September 23, 2026
Previous weekly editions.
  • Published September 23, 2026Evidence updated

    Sources added in this edition

    • 3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial
S7 Sciences

Effects of tesamorelin on non-alcoholic fatty liver disease in HIV: a randomised, double-blind, multicentre trial

The Lancet HIV

Published September 16, 2026
Previous weekly editions.
  • Published September 16, 2026Evidence updated

    Sources added in this edition

    • Effects of tesamorelin on non-alcoholic fatty liver disease in HIV: a randomised, double-blind, multicentre trial
S7 Sciences

Effects of liraglutide on ovarian dysfunction in polycystic ovary syndrome: a randomized clinical trial

Reproductive BioMedicine Online

Published September 16, 2026
Previous weekly editions.
  • Published September 16, 2026Evidence updated

    Sources added in this edition

    • Effects of liraglutide on ovarian dysfunction in polycystic ovary syndrome: a randomized clinical trial
S7 Sciences

Guidelines for Evaluating and Expressing the Uncertainty of NIST Measurement Results 1994 Edition

National Institute of Standards and Technology, Technical Note 1297

Published September 16, 2026
Previous weekly editions.
  • Published September 16, 2026Evidence updated

    Sources added in this edition

    • Guidelines for Evaluating and Expressing the Uncertainty of NIST Measurement Results 1994 Edition
S7 Sciences

MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis

Nature Communications

Published September 16, 2026
Previous weekly editions.
  • Published September 16, 2026Evidence updated

    Sources added in this edition

    • MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
S7 Sciences

Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension

Diabetes, Obesity and Metabolism

Published September 16, 2026
Previous weekly editions.
  • Published September 16, 2026Evidence updated

    Sources added in this edition

    • Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension

Semaglutide improved sperm morphology in obese men with type 2 diabetes mellitus and functional hypogonadism

Diabetes, Obesity and Metabolism

Published September 9, 2026
Previous weekly editions.
  • Published September 9, 2026Evidence updated

    Sources added in this edition

    • Semaglutide improved sperm morphology in obese men with type 2 diabetes mellitus and functional hypogonadism
    • FDA’s Concerns with Unapproved GLP-1 Drugs Used for Weight Loss

Effects of Kisspeptin Administration in Women With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial

JAMA Network Open

Published September 9, 2026
Previous weekly editions.
  • Published September 9, 2026Evidence updated

Guide for the Use of the International System of Units (SI)

National Institute of Standards and Technology, Special Publication 811

Published September 9, 2026
Previous weekly editions.
  • Published September 9, 2026Evidence updated

    Sources added in this edition

    • Guide for the Use of the International System of Units (SI)
    • NIST Guide to the SI, Chapter 8

Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial

The New England Journal of Medicine

Published September 9, 2026
Previous weekly editions.
  • Published September 9, 2026Evidence updated

Tirzepatide for Obesity Treatment and Diabetes Prevention

The New England Journal of Medicine

Published September 9, 2026
Previous weekly editions.
  • Published September 9, 2026Evidence updated

    Sources added in this edition

    • Tirzepatide for Obesity Treatment and Diabetes Prevention

Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial

JAMA Network Open via PubMed

Published September 2, 2026
Previous weekly editions.
  • Published September 2, 2026Text and sources unchanged
  • Published August 26, 2026Evidence updated

    Sources added in this edition

    • Chronic Subcutaneous Kisspeptin-10 Stimulates Gonadotropin Secretion for 12 Days in Healthy Men
  • Published August 19, 2026Text and sources unchanged
  • Published August 12, 2026Evidence updated

    Sources added in this edition

    • Dynamic modulation of LH secretion by continuous kisspeptin infusion in healthy men
  • Published August 7, 2026Archived edition

Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials

Obstetrics & Gynecology via PubMed

Published September 2, 2026
Previous weekly editions.
  • Published September 2, 2026Text and sources unchanged
  • Published August 26, 2026Text and sources unchanged
  • Published August 19, 2026Text and sources unchanged
  • Published August 12, 2026Text and sources unchanged
  • Published August 7, 2026Archived edition

Bacteriostatic Water for Injection, USP labeling

DailyMed / U.S. National Library of Medicine

Published September 2, 2026
Previous weekly editions.
  • Published September 2, 2026Text and sources unchanged
  • Published August 26, 2026Text and sources unchanged
  • Published August 19, 2026Text and sources unchanged
  • Published August 12, 2026Text and sources unchanged
  • Published August 5, 2026Text and sources unchanged
  • Published August 4, 2026Archived edition

Two-year effects of semaglutide in adults with overweight or obesity (STEP 5)

Nature Medicine via PubMed

Published September 2, 2026
Previous weekly editions.
  • Published September 2, 2026Evidence updated

    Sources added in this edition

    • FDA reminds compounders not to use dietary supplement grade glutathione for injectables
  • Published August 26, 2026Evidence updated

    Sources added in this edition

    • Optimal Balance Pharmacy Issues Voluntary Nationwide Recall of Certain Lots of Compounded Glutathione 200 mg/mL Multi-Dose Vials Due to Elevated Endotoxin Levels
  • Published August 19, 2026Evidence updated

    Sources added in this edition

    • Glutathione infusion before primary percutaneous coronary intervention: a randomised controlled pilot study
    • Victory Medical Center Pharmacy Issues Voluntary Nationwide Recall of Certain Lots of Compounded Glutathione 200 mg/mL Multi-Dose Vials Due to Elevated Endotoxin Levels
  • Published August 12, 2026Evidence updated

    Sources added in this edition

    • Efficacy and safety of retatrutide in people with type 2 diabetes (TRANSCEND-T2D-1): a randomized phase 3 trial
    • FDA’s Concerns with Unapproved GLP-1 Drugs Used for Weight Loss
  • Published August 5, 2026Text and sources unchanged
  • Published August 4, 2026Archived edition

Continued treatment with tirzepatide for maintenance of weight reduction (SURMOUNT-4)

JAMA via PubMed

Published September 2, 2026
Previous weekly editions.
  • Published September 2, 2026Text and sources unchanged
  • Published August 26, 2026Evidence updated

    Sources added in this edition

    • Chronic Subcutaneous Kisspeptin-10 Stimulates Gonadotropin Secretion for 12 Days in Healthy Men
  • Published August 19, 2026Text and sources unchanged
  • Published August 12, 2026Evidence updated

    Sources added in this edition

    • Efficacy and safety of retatrutide in people with type 2 diabetes (TRANSCEND-T2D-1): a randomized phase 3 trial
    • FDA’s Concerns with Unapproved GLP-1 Drugs Used for Weight Loss
  • Published August 5, 2026Text and sources unchanged
  • Published August 4, 2026Archived edition

Important boundary

Research education is not medical advice.

Articles describe published evidence and its limits. They do not provide dosing, administration, treatment, or cycling instructions. Consult a licensed physician for medical decisions.

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